Design thinking (DT) has recently re-emerged as an essential mindset and skillshift for modern organisations seeking to improve innovation performance in the fourth industrial revolution (4IR). However, despite recent popularity and success especially in the tech industry, DT has lacked critical academic engagement and scholarly enquiry especially in Africa. Hence, this paper sets out to provide empirical evidence on how DT can help create opportunities and innovation in an AI/Algorithm-driven 4IR era, and why the design curriculum in higher education should be updated to include DT competencies.